By 1771 Linnaeus finally named the tree Ginkgo Biloba which translates into “silver plume with two lobes.” In 1784, ginkgo was brought over to America to the garden of William Hamilton. The edible inner seed resembles an almond and is sold in Asian markets.USDA 2018, WHO 1999, The ginkgo species almost became extinct during the last ice age that began approximately 2 million years ago. Fresh (raw) or roasted ginkgo seeds and the unprocessed ginkgo leaves can contain dangerous amounts of a toxic substance. The widespread use of G. biloba extracts in clinical trials makes data from animal studies largely redundant. This is only a brief summary of general information about this product. The genus name Ginkgo is regarded as a misspelling of the Japanese gin kyo, “silver apricot”. It remains unclear whether ginkgo has a role in reducing the incidence of dementia in elderly patients or protecting against decline in cognitive function. Some trials included in the meta-analysis were of small sample size, and treatment duration was less than 3 months in each of the studies.Birks 2009, The effect of G. biloba on cognitive function in healthy individuals was examined in a systematic review and meta-analysis published in 2012, which concluded that no positive effect was evident for memory, executive function, or attention in 13 studies involving more than 2,500 participants.Laws 2012, Multiple other systematic reviews have been published, with many including subgroup analyses.Butler 2018, Cicero 2018 Clinical studies involving commercial industry generally report greater improvements in cognitive and neuropsychiatric measures.Gavrilova 2014, Ihl 2011, Napryeyenko 2007, Savaskan 2018, Von Gunten 2016, Yancheva 2009, A number of guidelines have been published on the use of ginkgo in Alzheimer disease and dementia. The species survived in China, where it was cultivated as a sacred tree, and it still decorates Buddhist temples throughout Asia. This is even true amongst people suffering from Raynaud’s Phenomona, a condition characterised by dangerously cold hands and feet. The GEM study (N=3,069 elderly men and women) preplanned an evaluation of cardiovascular outcomes and found no evidence that ginkgo 240 mg/day reduced total or cardiovascular mortality or cardiovascular events.Kuller 2010 A statistically significant positive finding was obtained for ginkgo in peripheral vascular disease; however, the number of events was too small to make any generalizations.Kuller 2010 Similarly, ginkgo did not reduce blood pressure in hypertensive or normotensive participants in the GEM study.Brinkley 2010 A 2009 Cochrane meta-analysis of 14 clinical trials evaluating the role of ginkgo in intermittent claudication found no evidence of a clinically important benefit in patients with peripheral arterial disease; the 2013 update reinforced this conclusion.Nicolaï 2009, Nicolai 2013 The American College of Cardiology Foundation/American Heart Association guidelines for the management of peripheral artery disease (2005/2011) state that the effectiveness of ginkgo in improving walking distance for patients with intermittent claudication is marginal and not well established (level B evidence).Anderson 2013, A Cochrane systematic review of studies to 2005, including 10 trials (N=792) assessing the efficacy of ginkgo, found no convincing evidence to support the use of ginkgo for recovery after stroke or for improvement in neurological deficit at the end of treatment.Zeng 2005, In a double-blind, randomized, placebo-controlled trial (N=102), significantly more patients in the ginkgo group achieved a 50% reduction in 4-month poststroke follow-up National Institutes of Health Stroke Scale (NIHSS) score compared with baseline than those in the placebo group (58.6% vs 18.5%, respectively; P<0.05).Oskouei 2013 In contrast, multivariate regression analysis of the trend of NIHSS scores from admission to follow-up revealed a significant decline in scores for G. biloba when adjusted for age and gender (P<0.05).Oskouei 2013. Czech: Jinan dvoulalocný, Ginkgo biloba. Consumption of the seeds may induce a toxic syndrome. Avoid products that contain other herbal remedies. turmeric, saw palmetto, garlic, echinacea. Common Name(s): 'Bryson City' Ginkgo; Ginkgo; Maiden Hairtree; Phonetic Spelling GING-ko bi-LOW-buh This plant has low severity poison characteristics. Ginkgo biloba, maidenhair tree, fossil tree - Philippine Herbal Medicine - An illustrated compilation of medicinal plants in the Philippines by Dr Godofredo Stuart, with botanical information, chemical properties, folkloric uses and medicinal research studies. View abstract. The fleshy layer and pulp have a foul, offensive odor and can cause contact dermatitis. Ginkgo preparations have been used for medicinal purposes for more than 1,000 years. Herbalists find that for men suffering from this type of impotence find relief with blood invigorating GBE. 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