Substance name : Glycol Ether PNB CAS-No. Propylenglycolmonobutylether ist eine farblose Flüssigkeit mit etherischem Geruch, die löslich in Wasser ist. The PPG stands for propylene glycol. Evaluation of potential human carcinogenicity of the synthetic monomer ethyl acrylate. Formulating with Glycol Ethers Article 1,2-Propylene glycol 1-monobutyl ether . Propylene glycol has been used for over 50 years in a large variety of applications. Below our list and specifications of propylene glycol ethers. The kidney and the liver were targets of PGMBE toxicity in rats. NIH commercially produced antiperspirants and e-cigarettes. Butyl Polyoxyalkylene Ethers (new data only) – Dec 2016 – Monice Fiume Reported Use - … 2004 Mar;(515):1-306. No Data, Some Concern . It is found in antifreeze, most. May generate flammable and/or toxic gases with alkali metals, nitrides, and other strong reducing agents. We supply many industries on a global basis. Dipropylene glycol monomethyl ether (also known as Methoxy Propoxy Propanol, Oxybispropanol, dipropylene glycol methyl ether, DPM, and Dowanol DPM) is a propylene oxide-based/P series glycol ether and has the formula C 7 H 16 O 3.It is a clear, colourless, viscous liquid which has a slight ether … Propylene glycol mono-t-butyl ether; Propylene glycol mono-t-butyl ether . Epub 2008 Oct 5. The PPG stands for propylene glycol. In our products, we use it as a cleaning agent that helps dissolve grease and soil from surfaces. OBJECTIVES: The increased use of glycol ethers (GEs) for water-based paints and cleaning products, combined with a lack of information about many of these products, particularly with regard to the effects of percutaneous exposure, led us to evaluate the skin absorption rates of a group of glycol ethers in vitro.METHODS: Skin permeation was calculated using the Franz cell method with human skin. Other Applications: The properties listed in the previous section also support the use of Glycol Ether PNB in agriculture, cosmetics, electronics, ink, textile and adhesive products. The Panel added Propylene Glycol Butyl Ether to the list of ingredients included in the RR. It is a component of cleaning formulations and of household and personal care products from which occupational and consumer exposure is likely. Tripropylene glycol mono n-butyl ether. It is a mixture of four isomers. Glycols are rarely found in nature but the simple structure especially of propylene glycols (i.e. Linear Formula CH 3 (CH 2) 3 OC 3 H 6 OH . DIPROPYLENE GLYCOL BUTYL ETHER . NTP technical report on the toxicology and carcinogenesis studies of propylene glycol mono-t-butyl ether (CAS No. Chronic E-Cigarette Exposure Alters the Human Bronchial Epithelial Proteome. NACRES NA.23 In mice of both sexes, the major target of PGMBE toxicity was the liver. Propylene Glycol Butyl Ether is the propylene glycol ether of n-butyl alcohol that conforms to the formula: C 7 H 16 O 2 Propylene glycol contains 3 carbon atoms, while butylene glycol is a little larger and contains 4 carbon atoms. Meeting report: summary of IARC monographs on formaldehyde, 2-butoxyethanol, and 1-tert-butoxy-2-propanol. Propylene glycol (1, 2-propanediol) is an organic compound (a diol alcohol) and is a tasteless, odorless and colorless clear oily liquid. Global Propylene Glycol N Butyl Ether Market is expected to grow at a CAGR x.x% over the next ten years, and will reach at US$ XX.X Mn in 2029, from US$ XX.X Mn in 2019 email inquiry@market.us phone +1 718 618 4351 (International) EC Number 225-878-4. Propylene glycol mono--butyl ether is used as a solvent in all-purpose cleaners, inks, and nail polish lacquers. These compounds are alkyl ethers which originate from either ethylene glycol (“E-series”) or propylene glycol (“P-series”). It is used as stabilizer for vitamins, and as a water-miscible cosolvent. It is majorly used in products that are used in treating metal and non-metal surfaces, laboratory products, and in water treatment formulation. For example, propylene glycol ethyl ether (PGEE) and its acetate do not cause the critical toxicities of testicular, thymic, or blood injury and do not produce birth defects. Cancer . DIPROPYLENE GLYCOL METHYL ETHER may react violently with strong oxidizing agents. Crit Rev Toxicol. It is used in a variety of coating, printing ink, and cleaning applications. Linear Formula CH 3 (CH 2) 3 OC 3 H 6 OC 3 H 6 OH . Dipropylene Glycol Butyl Ether is the propylene oxide-based glycol ether. Ethoxydiglycol, the ethyl ether of diethylene glycol, contains only one hydroxyl group. The category contains four structurally related propylene glycol ethers: Propylene Glycol n-Butyl Ether (PnB, 5131-66-8, ma jor (“alpha”) isomer, 29387-86-8 isomeric mixture) Dipropylene Glycol n-Butyl Ether (DPnB, 29911-28-2 major isomer or 35884-42-5 isomeric mixture)) propylene glycol monobutyl ether . Dipropylene Glycol Butyl Ether is manufactured by reacting Propylene Oxide with Butanol. : 5131-66-8 Formula : C7H16O2 Synonyms : 1-Butoxy-2-Propanol, Propylene Glycol (Mono) Butyl Ether, Propylene Glycol n-Butyl Ether; PNB 1.2. PubMed:Concentration and determination of the propylene glycol butyl ether esters of 2,4-dichlorophenoxyacetic acid (PGBE 2,4-D) in air. … The properties of Arcosolv PNB support its use in agricultural, coating, cleaning, ink, textile and adhesive products. In the 2-year study, the incidences of exposure-related hepatocellular adenoma, adenoma or carcinoma combined, and hepatoblastoma occurred with a positive trend, and were significantly increased in 1200 ppm groups. No Data, Some Concern . Belongs to the Following Reactive Group(s) Eastman™ PM Solvent (Propylene Glycol Monomethyl Ether), a medium-boiling glycol ether, is an active solvent for cellulose acetate butyrate, nitrocellulose, epoxy, phenolic, acrylic, and alkyd resins. Dipropylene Glycol Butyl Ether is the propylene oxide-based glycol ether. Dipropylene Glycol Butyl Ether is supplied as a product that is >98.5% pure. doi: 10.1371/journal.pbio.2003904. Butyl Glycol Ether Revision Date 03/04/2015 Version 1.0 Print Date 03/04/2015 110000002553 Page 2 of 9 SAFETY DATA SHEET Prevention P210 Keep away from heat/sparks/open flames/hot surfaces. Eigenschaften. LyondellBasell offers a broad line of glycol ethers based on ethylene and propylene. Dill JA, Lee KM, Renne RA, Miller RA, Fuciarelli AF, Gideon KM, Chan PC, Burka LT, Roycroft JH. Dipropylene glycol dimethyl ether. propylene glycol monobutylether . It is approved by the Food and Drug Administration as "an indirect and direct food additive for use as an antimicrobial agent, defoamer, stabilizer and component of adhesives", and also "may be used to wash or assist in the peeling of fruits and vegetables" and "may be safely used as components of articles intended for use in packaging, transporting & holding food". These solvents are widely used paints & coatings, industrial cleaners, and inks. Propylene glycol mono-t-butyl ether (PGMBE) is used as a solvent in a variety of commercial applications. Clipboard, Search History, and several other advanced features are temporarily unavailable. What’s so bad about PPG-14 butyl. Would you like email updates of new search results? Propylene glycol butyl ether ≥99% Synonym: DOWANOL ® PnB CAS Number 5131-66-8. alpha 2u-globulin nephropathy and renal tumors in national toxicology program studies. Cancer: 06/11/2004. 89399-28-0. Natl Toxicol Program Tech Rep Ser. Sassano MF, Davis ES, Keating JE, Zorn BT, Kochar TK, Wolfgang MC, Glish GL, Tarran R. PLoS Biol. tel.  |  Propylene glycol tertiary‐butyl ether (PGTBE) also has been tested and fails to elicit these toxicities or birth defects in rats exposed by inhalation to substantial concentrations. 1,2- and more so 1,3-propanediol) makes it very likely (I have to admit, I do not know for certain but think that it actually is the case) that these do indeed occur as side products in trace amounts for example in natural microbial metabolism. A colorless liquid with an ether-like odor. Male and female F344/N rats and B6C3F(1) mice were exposed to PGMBE by whole-body inhalation for 2 or 14 weeks (0, 75, 150, 300, 600, or 1200 ppm) or 2 years (0, 75, 300, or 1200 ppm); male NBR rats were exposed for 2 weeks. The National Institute of Standards and Technology (NIST) uses its best efforts to deliver a high quality copy of the Database and to verify that the data contained therein have been selected on the basis of sound scientific judgment. Now question is, what does 1,3-Propenediol metabolize to? It has low water solubility and good coupling and demonstrates good solvency for coating resins. Skin Allergies & Irritation . Recommended use and restrictions on use Use of the substance/mixture : Solvent 1.3. NLM It is a mixture of four isomers. Di(propylene glycol) butyl ether, mixture of isomers ≥98.5% Synonym: DOWANOL ® DPnB CAS Number 29911-28-2. • Ethylene glycol monomethyl ether (2-methoxyethanol, CH3OCH2CH2OH) 2004 Nov 15;204(2-3):123-40. doi: 10.1016/j.tox.2004.06.019. Get the latest public health information from CDC: https://www.coronavirus.gov, Get the latest research information from NIH: https://www.nih.gov/coronavirus, Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. C&L Inventory . It is found in antifreeze, most. commercially produced antiperspirants and e-cigarettes. Propylene glycol butyl ether, whose demand exceeded 400 kilo tons globally, held the largest market share in 2017. Propylene glycol (CH8O2) is a commonly used drug solubilizer in topical, oral, and injectable medications. Environ Health Perspect. Butylene Glycol, Hexylene Glycol and Dipropylene Glycol are aliphatic diols that function as solvents and viscosity decreasing agents in cosmetics and personal care products. 2003 Apr;72(2):223-34. doi: 10.1093/toxsci/kfg028. 57018-52-7) in F344/N rats and B6C3F1 mice and a toxicology study of propylene glycol mono-t-butyl ether in male NBR rats (inhalation studies). 59X1IJT82G. For example, propylene glycol ethyl ether (PGEE) and its acetate do not cause the critical toxicities of testicular, thymic, or blood injury and do not produce birth defects. 2007 Jun;35(4):533-40. doi: 10.1080/01926230701338941. We t studied the effects of propylene glycol mono-t-butyl ether on male and female rats and mice to identify potential toxic or cancer-related hazards to humans. Acts as a clear, odorless, light yellowish, mobile solvent for paints and printing inks. MDL number MFCD01781688. Is hypersensitivity pneumonitis work-related? ether? Sources/Uses. 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